1165841-46-2Relevant academic research and scientific papers
Selectivities in Nickel-Catalyzed Hydrocarboxylation of Enynes with Carbon Dioxide
Cao, Tao,Yang, Zheng,Ma, Shengming
, p. 4504 - 4508 (2017)
A three-component hydrocarboxylation of enynes with ZnEt2 and CO2 is realized. Highly selective cyclizative carboxylation of the C-C triple bond was observed. Preliminary mechanistic studies indicated both the concerted cyclometalation mechanism and the stepwise C=C bond-directed carboxylation were possible in this reaction.
Iron-catalyzed, hydrogen-mediated reductive cyclization of 1,6-enynes and diynes: Evidence for bis(imino)pyridine ligand participation
Sylvester, Kevin T.,Chirik, Paul J.
supporting information; experimental part, p. 8772 - 8774 (2009/12/04)
(Chemical Equation Presented) The bis(imino)pyridine iron dinitrogen complex (iPrPDI)Fe(N2)2 catalyzes the hydrogen-mediated reductive cyclization of enynes and diynes with turnover frequencies comparable to those of established precious metal catalysts. Amino, oxygenated, and carbon-based substrates are readily cyclized to the corresponding hetero- and carbocycles with 5 mol % iron and 4 atm H2 at 23°C. Stoichiometric reactions between selected substrates and the iron compound under a N2 atmosphere established transfer dehydrogenation from an isopropyl aryl substituent to either the enyne or diyne substrate. In situ monitoring of the catalytic reaction by 1H NMR spectroscopy coupled with deuterium labeling experiments established rapid cyclization followed by turnoverlimiting hydrogenation. Copyright
