116589-00-5Relevant academic research and scientific papers
Cyclization of Diketones to Pyridazine and Furan Derivatives
Allah, Hassan M. Faid,Soliman, Raafat
, p. 1745 - 1748 (2007/10/02)
Condensation of (+/-)-2,3-bis(3,4-dimethoxybenzoyl)butane-1,4-dione 1 with different hydrazine bases afforded the corresponding pyridazines 2 and 3.Refluxing the diketone 1 with methanolic hydrogen chloride yielded the corresponding 3,4-dimethylfuran derivative 5.Reaction of acetonylacetone 6 with p-sulfamylphenylhydrazine afforded the corresponding 3,6-dimethyl-1H-pyridazine derivative 7.Reaction of 7 with the appropriate isocyanate and isothiocyanate yielded the corresponding benzenesulfonylurea 8 and thiourea 9 derivatives respectively.The structures of the compounds synthesized were affirmed by microanalyses and spectral studies.
