116597-38-7Relevant academic research and scientific papers
General Synthesis of 2'(3')-O-Aminoacyl Oligoribonucleotides. The Protection of the Guanine Moiety
Hagen, Michael D.,Chladek, Stanislav
, p. 3189 - 3195 (2007/10/02)
The chemical synthesis of 2'(3')-O-aminoacyl oligoribonucleotides requires the development of a specific blocking scheme for all nucleoside components.Herein, we describe the synthesis of guanosine synthons protected at the O6-position with the
Synthesis of (2'(3')-O-(Aminoacyl) Trinucleotides Incorporating All Four Common Bases
Hagen, Michael D.,Scalfi-Happ, Claudia,Happ, Erwin,Chladek, Stanislav
, p. 5040 - 5045 (2007/10/02)
A general blocking system has been developed four common nucleosides that allows for a specific synthesis of 2'(3')-O-(aminoacyl) trinucleotides.The approach is exemplified by the synthesis of six 2'(3')-O-(L-phenylalanyl) trinucleotides (13) with sequenc
