116599-17-8 Usage
General Description
N-(5-Bromo-2-methylphenyl)methanesulfonamide is a chemical compound that is commonly used as a reagent in organic synthesis. It is a white crystalline solid that is soluble in organic solvents such as acetone, ethanol, and dimethyl sulfoxide. N-(5-Bromo-2-methylphenyl)methanesulfonamide is known for its ability to act as a nucleophile and as a source of bromine in organic reactions. It is also used as a building block in the synthesis of pharmaceuticals and agrochemicals. Additionally, N-(5-Bromo-2-methylphenyl)methanesulfonamide has been found to exhibit antibacterial and antifungal properties, making it a useful tool in medicinal chemistry research.
Check Digit Verification of cas no
The CAS Registry Mumber 116599-17-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,5,9 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 116599-17:
(8*1)+(7*1)+(6*6)+(5*5)+(4*9)+(3*9)+(2*1)+(1*7)=148
148 % 10 = 8
So 116599-17-8 is a valid CAS Registry Number.
116599-17-8Relevant articles and documents
Double C-H functionalization in sequential order: Direct synthesis of polycyclic compounds by a palladium-catalyzed C-H alkenylation-arylation cascade
Ohno, Hiroaki,Iuchi, Mutsumi,Kojima, Naoto,Yoshimitsu, Takehiko,Fujii, Nobutaka,Tanaka, Tetsuaki
supporting information; experimental part, p. 5352 - 5360 (2012/05/20)
Palladium-catalyzed cascade C-H alkenylation and arylation provides convenient access to polycyclic aromatic compounds. Treatment of 3-bromoaniline derivatives bearing a bromocinnamyl group on the nitrogen atom with a catalytic amount of [Pd(OAc)2] and PCy3aHBF4 in the presence of Cs2CO3 in dioxane affords naphthalene-fused indole derivatives in good yields. This double cyclization reaction is also applicable to heterocyclic substrates, giving fused indoles containing a heteroaromatic ring such as dibenzofuran, dibenzothiophene, carbazole, indole, or benzofuran through heterocyclic C-H arylation. When using a 2,6-unsubstituted aniline derivative, the first C-H arylation preferentially proceeds at the more hindered position of the aniline ring.
