116622-38-9

Basic information

• Product Name: L-Homocyclohexyl alanine
• Synonyms: L-Homocyclohexyl alanine;(S)-2-Amino-4-Cyclohexyl butanoic acid;(alphaS)-alpha-Aminocyclohexanebutanoic acid
• CAS NO: 116622-38-9
• Molecular Formula: C10H19NO2
• Molecular Weight: 185.26336
• EINECS: -0
• Mol File: 116622-38-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 321.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.054±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.33±0.10(Predicted)
• CAS DataBase Reference: L-Homocyclohexyl alanine(CAS DataBase Reference)
• NIST Chemistry Reference: L-Homocyclohexyl alanine(116622-38-9)
• EPA Substance Registry System: L-Homocyclohexyl alanine(116622-38-9)

Safety Data

• Hazardous Substances Data: 116622-38-9(Hazardous Substances Data)

Usage

General Description

L-Homocyclohexyl alanine is a type of non-proteinogenic amino acid. Non-proteinogenic amino acids refer to those that are not typically found in proteins but are nevertheless involved in various biological processes. Not much specific information is readily available regarding L-Homocyclohexyl alanine's properties or specific biological functions. However, like all amino acids, it plays a role in the chemical processes that occur within living organisms. L-Homocyclohexyl alanine is also chiral, meaning it has an asymmetric carbon atom that allows it to exist in multiple forms, each with different physical properties.

Upstream product

• 943-73-7 D-homophenylalanine 
• 21486-56-6 2-hydroxyimino-4-phenyl-butanoic acid 

Downstream Products

• 1206893-27-7 (2S,4S)-benzyl 4-(2-cyclohexylethyl)-5-oxo-2-phenyloxazolidine-3-carboxylate 

Relevant articles and documents

Discovery of potent iminoheterocycle BACE1 inhibitors

The synthesis of a series of iminoheterocycles and their structure-activity relationships (SAR) as inhibitors of the aspartyl protease BACE1 will be detailed. An effort to access the S3 subsite directly from the S1 subsite initially yielded compounds with sub-micromolar potency. A subset of compounds from this effort unexpectedly occupied a different binding site and displayed excellent BACE1 affinities. Select compounds from this subset acutely lowered Aβ40 levels upon subcutaneous and oral administration to rats.

Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups

Compounds of the formula STR1 in which R1 represents acyl substituted by a thio, sulphinyl or sulphonyl group, A represents an optionally N-alkylated α-amino acid residue that is bonded N-terminally to R1 and C-terminally to the grou