1166310-96-8

Basic information

• Product Name: 1-(3-chloropropyl)-3-[4-(1-naphthylmethoxy)phenyl]urea
• Synonyms: 1-(3-chloropropyl)-3-[4-(1-naphthylmethoxy)phenyl]urea
• CAS NO: 1166310-96-8
• Molecular Weight: 368.863
• Mol File: 1166310-96-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-chloropropyl)-3-[4-(1-naphthylmethoxy)phenyl]urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-chloropropyl)-3-[4-(1-naphthylmethoxy)phenyl]urea(1166310-96-8)
• EPA Substance Registry System: 1-(3-chloropropyl)-3-[4-(1-naphthylmethoxy)phenyl]urea(1166310-96-8)

Safety Data

• Hazardous Substances Data: 1166310-96-8(Hazardous Substances Data)

Upstream product

• 13010-19-0 3-Chloropropyl isocyanate 
• 212189-26-9 1-(4-aminophenoxymethyl)naphthalene 

Downstream Products

• 1166311-36-9 1-[4-(1-naphthylmethoxy)phenyl]tetrahydropyrimidin-2(1H)-one 

Relevant articles and documents

Studies on novel 2-imidazolidinones and tetrahydropyrimidin-2(1H)-ones as potential TACE inhibitors: Design, synthesis, molecular modeling, and preliminary biological evaluation

Compounds belonging to the class of 2-imidazolidinones and tetrahydropyrimidin-2(1H)-ones were synthesized and evaluated for their TACE inhibitory activity. Most of the compounds showed very good TACE inhibitory activity. Docking study clearly indicates importance of the P1′ group of the inhibitor for the TACE inhibitory activity. This work proves that these two classes of molecules could be used as potential leads for the development of TACE inhibitors.