116632-05-4

Basic information

• Product Name: 5-bromonaphthalen-2-ol
• Synonyms: 5-BroMo-2-naphthalenol;5-Bromonaphthalen-2-ol
• CAS NO: 116632-05-4
• Molecular Formula: C₁₀H₇BrO
• Molecular Weight: 223.06598
• Mol File: 116632-05-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 110-111 °C
• Boiling Point: 353.8±15.0 °C(Predicted)
• Appearance: /
• Density: 1.614±0.06 g/cm3(Predicted)
• PKA: 9.10±0.40(Predicted)
• CAS DataBase Reference: 5-bromonaphthalen-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromonaphthalen-2-ol(116632-05-4)
• EPA Substance Registry System: 5-bromonaphthalen-2-ol(116632-05-4)

Safety Data

• Hazardous Substances Data: 116632-05-4(Hazardous Substances Data)

Usage

Uses

5-Bromo-2-naphthalenol, can be used in the synthesis of substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. It is also used in the preparation of Fluoranthenes (F461990).

Upstream product

• 128557-02-8 4-bromo-7-methoxy-1,2-dihydronaphthalene 
• 83710-62-7 1-bromo-6-methoxynaphthalene 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 86-97-5 5-amino-2-naphthol 
• 13720-04-2 1,6-dibromonaphthalen-2-amine 
• 848574-11-8 7-bromo-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one 
• 19125-84-9 1,6-dibromonaphthalene 

Downstream Products

• 83710-62-7 1-bromo-6-methoxynaphthalene 
• 1353555-42-6 4-(5-(4-(t-butyl)phenyl)naphthalen-2-yl)-N,N-dimethylaniline 
• 1353556-80-5 C₂₉H₃₂N⁽¹⁺⁾ 
• 1353555-14-2 C₃₁H₂₇N 
• 1353633-31-4 C₂₈H₂₇NO₂ 
• 1353556-66-7 C₃₈H₄₅N₃O₄ 
• 1353556-47-4 C₂₈H₁₈F₂O 
• 1353556-39-4 5-(3-(benzyloxy)phenyl)naphthalene-2-ol 
• 1353555-49-3 C₃₀H₃₃NO₂*ClH 
• 1353556-70-3 N-(4-(5-(4-(t-butyl)phenyl)naphthalen-2-yl)-2,3-dimethoxyphenethyl)acetamide 
• 1353556-68-9 1-([1,1'-biphenyl]-3-yl)-6-(2-(bromomethyl)phenyl)naphthalene 
• 1353556-67-8 1-([1,1'-biphenyl]-3-yl)-6-(o-tolyl)naphthalene 
• 1353556-65-6 6-(2-(bromomethyl)phenyl)-1-(4-(tert-butyl)phenyl)napthalene 
• 1353556-64-5 1-(4-(t-butyl)phenyl)-6-(o-tolyl)naphthalene 

Relevant articles and documents

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Synthesis and Photochromism of Novel Pyridyl-Substituted Naphthopyrans

Multitarget synthetic strategies to access novel photochromic 3H-naphtho[2,1-b]pyrans decorated with pyridyl units are described. The new pyridyl-substituted 3H-naphtho[2,1-b]pyrans display good photochromic properties with reversible generation of photomerocyanines, which exhibit mainly orange/red hues. Photochromic parameters including photocolorability and persistence of color vary tremendously on structural modification of the naphthopyran core.

PYRAZOLE-CONTAINING MACROPHAGE MIGRATION INHIBITORY FACTOR INHIBITORS

In one aspect, the invention comprises compounds that bind and inhibit macrophage migration inhibitory factor. In another aspect, the invention provides methods of treating inflammatory disease, neurological disorders and cancer using the compounds of the invention.