116666-62-7

Basic information

• Product Name: benzyl [3-(2-benzimidazolyl)propyl]methylcarbamate
• Synonyms: benzyl [3-(2-benzimidazolyl)propyl]methylcarbamate
• CAS NO: 116666-62-7
• Molecular Weight: 323.395
• Mol File: 116666-62-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl [3-(2-benzimidazolyl)propyl]methylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl [3-(2-benzimidazolyl)propyl]methylcarbamate(116666-62-7)
• EPA Substance Registry System: benzyl [3-(2-benzimidazolyl)propyl]methylcarbamate(116666-62-7)

Safety Data

• Hazardous Substances Data: 116666-62-7(Hazardous Substances Data)

Downstream Products

• 64137-52-6 N-methyl-N-[3-(2-benzimidazolyl)propyl]amine 

Relevant articles and documents

Synthesis and evaluation of α,α′-disubstituted phenylacetate derivatives for T-type calcium channel blockers

We have synthesized and evaluated α,α′-disubstituted phenylacetate derivatives that were designed as T-type calcium channel blockers. Among them, compound 10e (IC50 = 8.17 ± 0.48 nM) showed the most potent T-type calcium current blocking activity and higher potency than Mibefradil (IC50 = 1.34 ± 0.49 μM). The PK profile and subtype selectivity over L-type calcium channel were satisfied for further animal assay using disease model.