1166820-03-6

Basic information

• Product Name: benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate
• Synonyms: benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate
• CAS NO: 1166820-03-6
• Molecular Weight: 309.365
• Mol File: 1166820-03-6.mol

Chemical Properties

• CAS DataBase Reference: benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate(1166820-03-6)
• EPA Substance Registry System: benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate(1166820-03-6)

Safety Data

• Hazardous Substances Data: 1166820-03-6(Hazardous Substances Data)

Upstream product

• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 286961-24-8 benzyl 1,2,3,6-tetrahydro-4-(trifluoromethylsulphonyloxy)-pyridine-1-carboxylate 
• 71597-85-8 (p-hydroxyphenyl)boronic acid 

Downstream Products

• 1240299-99-3 benzyl 4-[4-[3-(4-acetylpiperazin-1-yl)propoxy]phenyl]-5,6-dihydropyridine-1(2H)-carboxylate 
• 1240300-01-9 tert-butyl 4-[2-[4-(1-(benzyloxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)phenoxy]ethyl]piperazine-1-carboxylate 
• 62614-84-0 4-(4-hydroxyphenyl)-1,2,3,6-tetrahydropiperidine 
• 1869912-48-0 4-(piperidine-4-yl)phenol hydrobromide 
• 1869912-40-2 (R)-4-(2-(4-(1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)-1,3-dimethylpiperazin-2-one: 6-hydroxy-2-naphthoic acid(1:1) co-crystal 
• 203661-82-9 benzyl 4-(4-hydroxyphenyl)piperidine-1-carboxylate 
• 149377-19-5 4-(4-hydroxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1869912-39-9 (3R)?4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3?b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one 
• 1255340-05-6 6-(4-{4-[(1S)-2-(4-acetylpiperazin-1-yl)-1-(methoxymethyl)ethoxy]phenyl}piperidin-1-yl)-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine 
• 1255339-82-2 2-oxo-2-{4-[2-(4-{1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl}phenoxy)ethyl]piperazin-1-yl}ethanol 
• 1255339-36-6 1-cyclopropyl-4-[2-(4-{1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl}phenoxy)ethyl]piperazin-2-one 
• 1255339-99-1 6-(4-{4-[(1R)-2-(4-acetylpiperazin-1-yl)-1-methylethoxy]phenyl}piperidin-1-yl)-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine 

Relevant articles and documents

[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES

The invention concerns compounds of Formula (I) (Formula (I)) or pharmaceutically-acceptable salts thereof, wherein R1, R2 and n have any of the meanings defined herein before in the description; processes for their preparation, pharmaceutical compositions containing them and their use as anti-proliferative and/or cell-killing agents.

TRIAZOLO [4,3-B] PYRIDAZINE DERIVATIVES AND THEIR USES FOR PROSTATE CANCER

The invention concerns bicyclic compounds of Formula (I) wherein Formula (II), R1, R2, L1, L2, J, Y, k, n, p and r are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of androgen- receptor associated conditions, particularly prostate cancer.

[1,2,4] TRIAZOLO [4,3-B] PYRIDAZINES AS LIGANDS OF THE ANDROGEN RECEPTOR

The invention concerns bicyclic compounds of Formula (I): wherein, R1, R2, R3, R4, R5, X1, X2, Y, k, m, n and p are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of androgen- receptor associated conditions, particularly prostate cancer.