1166834-78-1Relevant articles and documents
Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide-p-aminobenzyl-amine linker system
Burke, Patrick J.,Toki, Brian E.,Meyer, David W.,Miyamoto, Jamie B.,Kissler, Kim M.,Anderson, Martha,Senter, Peter D.,Jeffrey, Scott C.
, p. 2650 - 2653 (2009)
Cytotoxic agents streptonigrin and 17-amino-geldanamycin were linked to monoclonal antibodies (mAbs), forming antibody-drug conjugates (ADCs) for antigen-mediated targeting to cancer cells. The drugs were conjugated with a linker construct that is labile