1167055-73-3 Usage
Uses
Used in Pharmaceutical Synthesis:
4-Oxazolecarboxylic acid, 2-bromo-, is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable building block for the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Synthesis:
4-Oxazolecarboxylicacid, 2-broMois also utilized in the synthesis of agrochemicals, contributing to the development of novel pesticides and other agricultural chemicals that can enhance crop protection and yield.
Used in Organic Synthesis:
As a versatile building block, 4-Oxazolecarboxylic acid, 2-bromo-, is employed in organic synthesis for the preparation of various organic compounds, including complex molecules and functional materials.
Used in Medicinal Chemistry and Drug Discovery:
4-Oxazolecarboxylicacid, 2-broMo-'s potential biological activities and therapeutic properties have made it an attractive candidate for medicinal chemistry research and drug discovery. It can be used to design and develop new drugs targeting specific diseases and conditions.
Used in Research and Development:
4-Oxazolecarboxylic acid, 2-bromo-, is also used in research and development laboratories for studying its chemical properties, reactivity, and potential applications in various fields, including materials science, catalysis, and environmental chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1167055-73-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,7,0,5 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1167055-73:
(9*1)+(8*1)+(7*6)+(6*7)+(5*0)+(4*5)+(3*5)+(2*7)+(1*3)=153
153 % 10 = 3
So 1167055-73-3 is a valid CAS Registry Number.
1167055-73-3Relevant academic research and scientific papers
Widely Exploited, Yet Unreported: Regiocontrolled Synthesis and the Suzuki–Miyaura Reactions of Bromooxazole Building Blocks
Solomin, Vitalii V.,Radchenko, Dmytro S.,Slobodyanyuk, Evgeniy Y.,Geraschenko, Oleksandr V.,Vashchenko, Bohdan V.,Grygorenko, Oleksandr O.
, p. 2884 - 2898 (2019/03/07)
An approach to synthesis of 2-, 4-, and 5-bromooxazoles is described. The method was optimized, and its scope was extended to all three isomeric parents, as well as various alkyl- and aryl-substituted bromooxazoles. It was found that direct regiocontrolled lithiation followed by reaction with electrophilic bromine source was common for all substrates and led exclusively to the target substituted 2-, 4- and 5-bromooxazoles on multigram scale. The utility of the multipurpose building blocks obtained in this work was demonstrated in the Suzuki–Miyaura cross-coupling reaction under parallel synthesis conditions.
ANDROGEN RECEPTOR MODULATING COMPOUNDS
-
Page/Page column 152, (2011/05/11)
Compounds of formula (I) wherein R1 to R16, A. B and E are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds of formula (I) possess utility as tissue-selective androgen receptor modulators (SARM) and are particularly useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.
