116741-63-0

Upstream product

• 36321-90-1 2-methoxy-1-naphthylmagnesium bromide 
• 127721-16-8 (S)-1-phenylethyl 1-methoxy-2-naphthoate 
• 1445-91-6 (S)-1-phenylethanol 
• 116741-62-9 (aS)-2'-methoxy-1,1'-binaphthyl-2-carbonyl chloride 
• 6039-59-4 methyl 1-methoxy-2-naphthoate 
• 148089-36-5 1-(d-p-menth-3-yloxy)-2-naphthoic acid 
• 129656-75-3 1-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-naphthalene-2-carboxylic acid (R)-1-phenyl-ethyl ester 
• 1517-69-7 (R)-1-phenylethanol 
• 129656-73-1 (-)-menthyl 1-(-)-menthyloxy-2-naphthoate 
• 148089-35-4 1-(l-p-menth-3-yloxy)-2-naphthoic acid 

Relevant academic research and scientific papers

Use of a racemic derivatizing agent for measurement of enantiomeric excess by circular dichroism spectroscopy

Enantiomeric excesses of several alcohols and an amine have been determined by derivatization with racemic 2′-methoxy-1,1′-binaphthyl-2-carbonyl chloride rac-1, with no requirement for kinetic resolution in the acylation step. The necessary information is provided instead by CD and UV spectra of the derived esters and amides, the chiral signal being dominated by the binaphthyl component.

Nucleophilic Aromatic Substitution on 1-Alkoxy-2-naphthoates with 1-Naphthyl Grignard Reagents. A Practical and Convenient Asymmetric Synthesis of 1,1'-Binaphthyl-2-carboxylates

1-Naphthyl Grignard reagents efficiently displace the 1-alkoxyl group of 1-alkoxy-2-naphthoic esters to provide an easy access to the corresponding 1,1'-binaphthyl-2-carboxylates in excellent yields; isopropyl ester is bulky enough to prevent the Grignard

An Efficient Asymmetric Synthesis of Atropisomeric 1,1'-Binaphthyls via Nucleophilic Aromatic Substitution Reaction

High levels of asymmetric induction (up to 98percent optical yield) were achieved in the joining of two naphthalene rings by the nucleophilic displacement of 1-menthoxyl group of 1-(-)-menthoxy-2-naphthoates (1) with 1-naphthyl Grignard reagents.Also repo

Facile Synthesis of 1,1'-Binaphthyl-2-carboxylates via Nucleophilic Aromatic Substitution of 1-Methoxy-2-naphthoic Esters by 1-Naphthyl Grignard Reagents

Grignard reagents formed from 1-bromonaphthalenes smoothly displaced the 1-methoxyl group of 1-methoxy-2-naphthoic esters to provide a facile route of 1,1'-binaphthyl-2-carboxylic acids in excellent yields; the reaction of (S)-1-phenylethyl esters caused