1167443-65-3Relevant academic research and scientific papers
Soluble polymer supported 2-imidazolidinone chiral auxiliary and method for manufacturing the same
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Paragraph 0068, (2017/01/02)
The present invention relates to a chiral auxiliary agent and a manufacturing method thereof and, more specifically, to a 2-imidazolidinone chiral auxiliary agent supported onto a polymer soluble in an organic solvent and a manufacturing method thereof. The chiral auxiliary agent in the present invention shows effects of being easy to separate reaction products and the chiral auxiliary agent after a termination of a reaction while fulfilling an economic efficacy of chiral auxiliary molecules by being supported onto the polymer soluble in the organic solvent.COPYRIGHT KIPO 2015
Solid phase asymmetric alkylation reactions using 2-imidazolidinone chiral auxiliary
Nguyen, Quynh Pham Bao,Kim, Jae Nyoung,Kim, Taek Hyeon
scheme or table, p. 4015 - 4018 (2009/11/30)
A novel solid supported 2-imidazolidinone chiral auxiliary was prepared from O-benzyl-l-tyrosine and Wang resin. Asymmetric alkylation reactions in the solid phase proceeded with excellent stereoselectivities, which were even higher than those observed in the conventional solution phase method.
