Azido-PEG12-acid is an aqueous soluble, monodisperse PEG reagent that features an azide group with a terminal carboxylic acid. This versatile molecule is capable of engaging in Click Chemistry reactions with alkyne, BCN, and DBCO due to its azide group, while its terminal carboxylic acid allows it to form stable amide bonds with primary amine groups in the presence of activators such as EDC or HATU.
1167575-20-3
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Basic information
- Product Name: Azido-PEG12-acid
- Synonyms: Azido-PEG24-acid;Azido-PEG12-acid;Azido-PEG13-acid;N3-PEG12-CH2CH2COOH;Azido-PEG12-propionic acid;N3-PEG12-COOH;Azide-PEG12-COOH;Azido-dPEG(R)12-acid
- CAS NO:1167575-20-3
- Molecular Formula: C27H53N3O14
- Molecular Weight: 643.72142
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1167575-20-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20°C
- Solubility: Soluble in Water, DMSO, DCM, DMF
- CAS DataBase Reference: Azido-PEG12-acid(CAS DataBase Reference)
- NIST Chemistry Reference: Azido-PEG12-acid(1167575-20-3)
- EPA Substance Registry System: Azido-PEG12-acid(1167575-20-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1167575-20-3(Hazardous Substances Data)
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1167575-20-3 Usage
Uses
Used in Bioconjugation:Azido-PEG12-acid is used as a bioconjugation agent for the attachment of various biomolecules to other molecules or surfaces. Its ability to form stable amide bonds with primary amines makes it a reliable choice for creating covalent linkages in a controlled manner.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Azido-PEG12-acid is utilized as a component in drug delivery systems. Its reactivity with both azide and carboxylic acid groups enables the development of targeted drug carriers that can be tailored to specific therapeutic applications.
Used in Materials Science:
Azido-PEG12-acid is employed as a building block in the synthesis of functional materials. Its compatibility with Click Chemistry allows for the creation of complex structures with precise control over molecular architecture, which is valuable in various high-tech applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, Azido-PEG12-acid serves as a versatile intermediate for the preparation of a wide range of PEGylated compounds. Its reactivity and solubility make it an attractive candidate for the development of new chemical entities with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1167575-20-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,7,5,7 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.Calculate Digit Verification of CAS Registry Number 1167575-20:
(9*1)+(8*1)+(7*6)+(6*7)+(5*5)+(4*7)+(3*5)+(2*2)+(1*0)=173
173 % 10 = 3
So 1167575-20-3 is a valid CAS Registry Number.
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1167575-20-3Downstream Products
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Azido-PEG12-acid
