116782-56-0

Basic information

• Product Name: threo-(2S,3S)-3-(hydroxymethyl)-2-(4-nitrophenyl)-1-oxa-4-azaspiro[4.5]decane
• Synonyms: threo-(2S,3S)-3-(hydroxymethyl)-2-(4-nitrophenyl)-1-oxa-4-azaspiro[4.5]decane
• CAS NO: 116782-56-0
• Molecular Weight: 292.335
• Mol File: 116782-56-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: threo-(2S,3S)-3-(hydroxymethyl)-2-(4-nitrophenyl)-1-oxa-4-azaspiro[4.5]decane(CAS DataBase Reference)
• NIST Chemistry Reference: threo-(2S,3S)-3-(hydroxymethyl)-2-(4-nitrophenyl)-1-oxa-4-azaspiro[4.5]decane(116782-56-0)
• EPA Substance Registry System: threo-(2S,3S)-3-(hydroxymethyl)-2-(4-nitrophenyl)-1-oxa-4-azaspiro[4.5]decane(116782-56-0)

Safety Data

• Hazardous Substances Data: 116782-56-0(Hazardous Substances Data)

Upstream product

• 119-62-0 (1S,2S)-2-amino-1-(4-nitrophenyl)propane-1,3-diol 
• 108-94-1 cyclohexanone 

Downstream Products

• 18531-99-2 (S)-[1,1']-binaphthalenyl-2,2'-diol 

Relevant articles and documents

Regioselectivity of the interaction of (1s,2s)-2-amino-1-(4-nitrophenyl)-1, 3-propanediol with some symmetrical ketones

The interaction of (1S,2S)-2-amino-1-(4-nitrophenyl)-1,3-propanediol with a series of symmetrical ketones has been studied. As a result isomeric oxazolidines are formed in a ratio of 85:15. These oxazolidines were shown to decompose readily under the action of hydrazine.

A highly efficient chemoselective cyclocondensation of threo-(1S,2S)-2-amino-1-(4-nitrophenyl)-1,3-propanediol with ketones and isomerization of the condensates

A convenient procedure for highly efficient chemoselective cyclization of threo-(1S.2S)-2-amino-1-(4-nitrophenyl)propane-1,3-diol with some ketones was described. The structures of the condensates were elucidated on the basis of the IR, 1H- and