1168-15-6

Usage

Uses

Used in Pharmaceutical Applications:
(2E)-1-(1-oxidoquinolin-4-yl)-2-(1-oxoquinolinium-4(1H)-ylidene)hydrazinolate is used as a pharmaceutical compound for its potential therapeutic properties. Its unique structure may contribute to the development of new drugs, particularly in the treatment of various diseases and conditions.
Used in Materials Science:
In the field of materials science, (2E)-1-(1-oxidoquinolin-4-yl)-2-(1-oxoquinolinium-4(1H)-ylidene)hydrazinolate is used as a component in the development of novel materials. Its specific properties may enable the creation of advanced materials with unique characteristics for various applications.
Used in Organic Synthesis:
(2E)-1-(1-oxidoquinolin-4-yl)-2-(1-oxoquinolinium-4(1H)-ylidene)hydrazinolate is utilized as a reagent or intermediate in organic synthesis processes. Its reactivity and structural features make it a valuable component in the synthesis of other complex organic compounds.
Further research is necessary to fully explore the potential applications and capabilities of (2E)-1-(1-oxidoquinolin-4-yl)-2-(1-oxoquinolinium-4(1H)-ylidene)hydrazinolate, as its complex nature presents numerous possibilities for innovation and discovery across different industries.

Upstream product

• 18061-48-8 1-acetoxy-4-(acetoxyimino)-1,4-dihydroquinoline 
• 2669-36-5 4-quinolyl azide N-oxide 
• 4637-59-6 4-Chloroquinoline N-oxide 
• 4637-56-3 4-(hydroxyamino)quinoline N-oxide 

Relevant academic research and scientific papers

4-Azidoquinoline N-oxide: Synthesis and photolysis

In photolysis of 4-azidoquinoline N-oxide azoxy compound was isolated as the final reaction product. This result may be ascribed to the dimerization of the intermediate nitrene to azo compound followed by oxidation of the latter with air oxygen. The initially arising nitrene is stabilized by resonance conjugation involving the aromatic system and the N-oxide group. The rate constants of 4-azidoquinoline N-oxide photolysis were measured in various solvents and the values of spin density and bond lengths in the formed nitrene were calculated.

On the photochemistry of 4-azidoquinoline 1-oxide: Structural elucidation of primary photoproduct

The primary product of the photolysis of 4-azidoquinoline 1-oxide (1) is believed to be the azo-dimer (4), consistent with the photochemistry of the pyridine analogue (2). This species has not been unambiguously identified, and previous workers have only isolated various isomers of the azoxy species (5). A combined IR, NMR, LC/MS and computational study confirms the structure 4 as the primary product of photolysis of 1 at 355 nm, suggesting that 5 arises from secondary photochemistry of 4.

Concerning Model Metabolites of the Carcinogen 4-Nitroquinoline 1-Oxide. Reactivity of 1-Acetoxy-4-(hydroxyimino)-1,4-dihydroquinoline

1-Acetoxy-4-(hydroxyimino)-1,4-dihydroquinoline is obtained by hydrolysis of 1-acetoxy-4-(acetoxyimino)-1,4-dihydroquinoline under strongly acidic conditions.At pH 1 the monoacetate is protonated and on hydrolysis affords only 1-hydroxy-4-(hydroxyimino)-1,4-dihydroquinoline.Above pH 1 on hydrolysis the monoacetate affords a complex product mixture including 4-(hydroxyamino)quinoline and 4-nitrosoquinoline.Comparison of the above behavior of 1-acetoxy-4-(hydroxyamino)-1,4-dihydroquinoline with that of 1-hydroxy-4-(acetoxyimino)-1,4-dihydroquinoline at a neutral pH suggests that the former type of ester is less likely to be important in those steps initiating oncogenesis.In contrast the latter type of monoester or diesters corresponding to 1-acetoxy-4-(acetoxyimino)-1,4-dihydroquinoline by their ability to generate nitrenium ion intermediates and undergo attack by nucleophiles at the 3-position are likely intermediates in the process of oncogenesis.Further aspects of their likely biological role are discussed.