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[2,6-dimethyl-4-(triisopropylsilanyloxy)phenyl](2-isobutylpyridin-4-yl)methanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1168136-35-3

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1168136-35-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1168136-35-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,8,1,3 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1168136-35:
(9*1)+(8*1)+(7*6)+(6*8)+(5*1)+(4*3)+(3*6)+(2*3)+(1*5)=153
153 % 10 = 3
So 1168136-35-3 is a valid CAS Registry Number.

1168136-35-3Relevant academic research and scientific papers

Selective chemical rescue of a thyroid-hormone-receptor mutant, TRβ(H435Y), identified in pituitary carcinoma and resistance to thyroid hormone

Hassan, A. Quamrul,Koh, John T.

supporting information; experimental part, p. 7280 - 7283 (2009/04/20)

(Figure Presented) Ligand to the rescue! Thyroid hormone receptor (TR) plays a critical role in development and homeostasis. The mutant TRβ(H435Y) was identified in both cancer and resistance to thyroid hormone. A designed synthetic ligand recovered the cellular reporter-gene activity of TRβ(H435Y) with a 5850-fold improvement in selectivity for the mutant relative to that of the natural hormone T3 (shown in a modeled structure with TRβ-(H435Y)).

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