116830-34-3

Basic information

• Product Name: (-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-butyl-2-pyrrolidine
• Synonyms: (-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-butyl-2-pyrrolidine
• CAS NO: 116830-34-3
• Molecular Weight: 247.381
• Mol File: 116830-34-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-butyl-2-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-butyl-2-pyrrolidine(116830-34-3)
• EPA Substance Registry System: (-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-butyl-2-pyrrolidine(116830-34-3)

Safety Data

• Hazardous Substances Data: 116830-34-3(Hazardous Substances Data)

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 4316-44-3 4-oxooctanoic acid 
• 158271-95-5 1-(2-hydroxy-1-phenylethyl)-1,5-dihydropyrrol-2-one 
• 133007-27-9 (3R,7aS)-3-phenyl-2,3,5,6,7,7a-hexahydropyrrolo[2,1-b]oxazol-5-one 
• 362045-69-0 (5R)-butyl-1-(2-hydroxy-(1'R)-phenylethyl)-pyrrolidin-2-one 
• 132959-43-4 (-)-(3R,7aS)-3-Phenyl-5-oxo-7a-butyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole 

Relevant articles and documents

Asymmetric synthesis of 5-substituted pyrrolidinones via a chiral N-acyliminium equivalent

5-Substituted pyrrolidinones 5 were synthesized in good yields and with fair to good diastereoselectivities from the chiral non-racemic oxazolopyrrolidinone 4. Various nucleophiles including cuprates, silanes and phosphites were used. The chiral induction

A Simple Asymmetric Synthesis of 2-Substituted Pyrrolidines and 5-Substituted Pyrrolidinones

An efficient procedure for the preparation of the title compounds in high enantiomeric purity has been realized starting from 3-acylpropionic acids.Stereoselective reduction of chiral bicyclic lactams 2a-h, prepared from the corresponding γ-keto acid and

ASYMMETRIC SYNTHESIS XIII SYNTHESIS OF 2-ALKYLPYRROLIDINES : TOWARDS AZABICYCLIC SYSTEMS

The enantiospecific synthesis of a series of 2(S)-alkylpirrolidines from 2-cyano oxazolopyrrolidine synthon 1 is described.Two of the synthesised compunds represent key intermediates towards azabicyclic alkaloids.