116850-73-8

Basic information

• Product Name: Benzoic acid, 2-fluoro-, 2-[(methylamino)thioxomethyl]hydrazide
• Synonyms: 2-(2-fluorobenzoyl)-N-methyl-1-hydrazinecarbothioamide
• CAS NO: 116850-73-8
• Molecular Formula: C₉H₁₀FN₃OS
• Molecular Weight: 227.26
• Mol File: 116850-73-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 2-fluoro-, 2-[(methylamino)thioxomethyl]hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-fluoro-, 2-[(methylamino)thioxomethyl]hydrazide(116850-73-8)
• EPA Substance Registry System: Benzoic acid, 2-fluoro-, 2-[(methylamino)thioxomethyl]hydrazide(116850-73-8)

Safety Data

• Hazardous Substances Data: 116850-73-8(Hazardous Substances Data)

Upstream product

• 6610-29-3 4-methylthiosemicarbazide 
• 393-52-2 2-Fluorobenzoyl chloride 
• 446-24-2 2-fluorobezohydrazide 
• 556-61-6 methyl thioisocyanate 

Downstream Products

• 114058-90-1 5-(2-Fluorophenyl)-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione 
• 116850-66-9 3-Ethanesulfonyl-5-(2-fluoro-phenyl)-4-methyl-4H-[1,2,4]triazole 
• 116850-65-8 3-Ethanesulfinyl-5-(2-fluoro-phenyl)-4-methyl-4H-[1,2,4]triazole 
• 116850-47-6 3-(2-fluorophenyl)-4-methyl-5-methylsulfonyl-4H-1,2,4-triazole 
• 116850-46-5 4-methyl-3-(2-fluorophenyl)-5-ethylthio-4H-1,2,4-triazole 
• 116850-53-4 3-(2-fluorophenyl)-4-methyl-5-methylsulfinyl-4H-1,2,4-triazole 
• 116850-50-1 5-(2-fluorophenyl)-4-methyl-3-methylthio-4H-1,2,4-triazole 

Relevant articles and documents

Long-Range Fluorine-Proton Coupling in 1,2,4-Triazole Derivatives

Several 1,2,4-triazole derivatives containing a 2-fluorophenyl substituent at either the 3- or 5-position and a methyl group at the 4-position were synthesized.These derivatives exhibit long-range 19F-1H and 19F-13C through-space coupling in their 1H and

5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents

Selected examples from three series of isomeric (alkylthio)-1,2,4- triazoles were prepared and examined for anticonvulsant activity versus strychnine-, maximal-electroshock-, pentylenetetrazole-, and 3- mercaptopropionic-acid-induced seizures in mice. A n

3-aryl-5-alkylthio-4H-1,2,4-traizoles for treatment of hyperreflexia due to spinal trauma

This invention relates to the use of 3-aryl-5-alkylthio-4H-1,2,4-triazoles and the corresponding alkylsulfinyl- and alkylsulfonyl-4H-1,2,4-triazoles in the treatment of patients suffering from chronic hyperreflexia due to spinal trauma.

3-aryl-5-alkylthio-4H-1,2,4-triazoles

This invention relates to novel sulfone and sulfoxide derivatives of 3-aryl-5-alkylthio-4H-1,2,4-triazoles and to the use of 3-aryl-5-alkylthio-, alkylsulfinyl- and alkylsulfonyl-4H-1,2,4-triazoles in the treatment of patients suffering from convulsant seizures.

3-aryl-5-alkylthio-4H-1,2,4-triazoles

This invention relates to derivatives of 3-aryl-5-alkylthio-4H-1,2,4-triazoles, to their pharmacological properties and to their use as muscle relaxants, spasmolytics, anticonvulsants and anxiolytics.

2,4-Dihydro-3H-1,2,4-triazole-3-thiones as Potential Antidepressant Agents

A series of 5-aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones was prepared and evaluated for potential antidepressant activity.Members of this series were generally prepared by the alkaline ring closures of the corresponding 1-aroylthiosemicarbazides.Several