116864-55-2

Basic information

• Product Name: (S)-3-(N-Tritylamino)-2-pyrrolidon
• Synonyms: (S)-3-(N-Tritylamino)-2-pyrrolidon
• CAS NO: 116864-55-2
• Molecular Weight: 342.44
• Mol File: 116864-55-2.mol

Chemical Properties

• CAS DataBase Reference: (S)-3-(N-Tritylamino)-2-pyrrolidon(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(N-Tritylamino)-2-pyrrolidon(116864-55-2)
• EPA Substance Registry System: (S)-3-(N-Tritylamino)-2-pyrrolidon(116864-55-2)

Safety Data

• Hazardous Substances Data: 116864-55-2(Hazardous Substances Data)

Upstream product

• 116864-54-1 [3-Carbamoyl-3-(trityl-amino)-propyl]-dimethyl-sulfonium; iodide 
• 116864-53-0 Trityl-L-methioninamid 

Downstream Products

• 1883-09-6 L-2,4-Diaminobuttersaeure-dihydrochlorid 

Relevant articles and documents

Application of N-Tritylmethionine in the Preparation of Heterocycles of Biological and Synthetic Interest

Treatment of the methylsulfonium salts of the corresponding N-tritylmethionine derivatives with sodium hydride or potassium tert-butoxide provides the heterocycles N-trityl-L-homoserine lactone (3), (S)- and (R)-3-(N-tritylamino)tetrahydrofuran (7a, 7b), (S)-1-hydroxy-3-(N-tritylamino)-2-pyrrolidinone (14), (S)-4-(N-tritylamino)-1,2-oxazinan-3-one (15), (S)-3-(N-tritylamino)-2-pyrrolidone (23), (S)-1-tert-butyloxycarbonylamino-3-(N-tritylamino)-2-pyrrolidone (27), and (S)-2-methyl-4-(N-tritylamino)-1,2-oxazinan-3-one (18).Methylation of 14 and 15 yields (S)-1-methoxy-3-(N-tritylamino)-2-pyrrolidone (17) and 18, respectively.The stereochemistry of compounds 3, 7a, and 17 has been determined by X-ray crystal structure analysis.