116870-77-0

Basic information

• Product Name: 3-(2-aminophenyl)-2-{2-[(1-methylethyl)amino]ethyl}-2,3-dihydro-1H-isoindol-1-one (2E)-but-2-enedioate
• CAS NO: 116870-77-0
• Molecular Formula: C₂₃H₂₇N₃O₅
• Molecular Weight: 425.4776
• Mol File: 116870-77-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 473.5°C at 760 mmHg
• Flash Point: 240.2°C
• Vapor Pressure: 3.91E-09mmHg at 25°C
• CAS DataBase Reference: 3-(2-aminophenyl)-2-{2-[(1-methylethyl)amino]ethyl}-2,3-dihydro-1H-isoindol-1-one (2E)-but-2-enedioate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-aminophenyl)-2-{2-[(1-methylethyl)amino]ethyl}-2,3-dihydro-1H-isoindol-1-one (2E)-but-2-enedioate(116870-77-0)
• EPA Substance Registry System: 3-(2-aminophenyl)-2-{2-[(1-methylethyl)amino]ethyl}-2,3-dihydro-1H-isoindol-1-one (2E)-but-2-enedioate(116870-77-0)

Safety Data

• Hazardous Substances Data: 116870-77-0(Hazardous Substances Data)

Relevant articles and documents

Isoindolin-1-one derivative and antiarrhythmic agent

Isoindolin-1-one compounds represented by the following formula (I); STR1 {wherein n represents an integer of 1 to 6; m represents 0 or 1; R1, R2 and R3 are each independently hydrogen or lower alkyl, and when m is 1, R1 and one of R2 and R3 may form a five-membered or six-membered ring over N atom; X represents hydrogen or hydroxy; Ar represents naphthyl, pyridyl or substituted phenyl represented by the formula (II); Ar and X may form a lactone ring; STR2 [wherein Y represents carboxyl, lower alkoxycarbonyl, carbamoyl, N,N-lower alkyl-substituted carbamoyl or amino represented by the formula (III): STR3 (wherein R6 and R7 are each independently hydrogen, lower alkyl or lower alkanoyl); R4 and R5 are each independently hydrogen, lower alkyl, cyano or halogen]} or a pharmaceutically acceptable acid addition salt or metal salt thereof have an excellent antiarrhythmic activity.