116941-04-9

Basic information

• Product Name: Ethyl (cis-4-hydroxycyclohexyl)acetate
• Synonyms: cyclohexaneacetic acid, 4-hydroxy-, ethyl ester, cis-
• CAS NO: 116941-04-9
• Molecular Formula: C₁₀H₁₈O₃
• Molecular Weight: 186.2481
• Mol File: 116941-04-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 268.173°C at 760 mmHg
• Flash Point: 106.153°C
• Density: 1.049g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.471
• CAS DataBase Reference: Ethyl (cis-4-hydroxycyclohexyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl (cis-4-hydroxycyclohexyl)acetate(116941-04-9)
• EPA Substance Registry System: Ethyl (cis-4-hydroxycyclohexyl)acetate(116941-04-9)

Safety Data

• Hazardous Substances Data: 116941-04-9(Hazardous Substances Data)

Upstream product

• 17138-28-2 (4-hydroxy-phenyl)-acetic acid ethyl ester 

Relevant articles and documents

Trans-Selective and Switchable Arene Hydrogenation of Phenol Derivatives

A trans-selective arene hydrogenation of abundant phenol derivatives catalyzed by a commercially available heterogeneous palladium catalyst is reported. The described method tolerates a variety of functional groups and provides access to a broad scope of trans-configurated cyclohexanols as potential building blocks for life sciences and beyond in a one-step procedure. The transformation is strategically important because arene hydrogenation preferentially delivers the opposite cis-isomers. The diastereoselectivity of the phenol hydrogenation can be switched to the cis-isomers by employing rhodium-based catalysts. Moreover, a protocol for the chemoselective hydrogenation of phenols to cyclohexanones was developed.