1169762-19-9

Basic information

• Product Name: C₂₆H₃₆BrFN₄O₄
• Synonyms: C₂₆H₃₆BrFN₄O₄
• CAS NO: 1169762-19-9
• Molecular Weight: 567.499
• Mol File: 1169762-19-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₆BrFN₄O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₆BrFN₄O₄(1169762-19-9)
• EPA Substance Registry System: C₂₆H₃₆BrFN₄O₄(1169762-19-9)

Safety Data

• Hazardous Substances Data: 1169762-19-9(Hazardous Substances Data)

Upstream product

• 913543-99-4 tert-butyl 2-cyano-3,3-bis(methylthio)acrylate 
• 747392-34-3 1-(2-bromo-5-fluorophenyl)methanamine 
• 1169762-17-7 tert-butyl 3-{(3R)-3-[(tert-butoxycarbonyl)amino]-3-methylpiperidin-1-yl}-2-cyano-3-(methylthio)acrylate 
• 1169762-18-8 (3R)-3-[(tert-butoxycarbonyl)amino]-3-methylpiperidine 

Downstream Products

• 1169762-21-3 4-tert-butyl 2-ethyl 3-amino-1-(2-bromo-5-fluorobenzyl)-5-{(3R)-3-[(tert-butoxycarbonyl)amino]-3-methylpiperidin-1-yl}-1H-pyrrole-2,4-dicarboxylate 
• 1169762-20-2 C₃₀H₄₂BrFN₄O₆ 

Relevant articles and documents

Convenient synthesis of 4-tert-butyl 2-ethyl 3-amino-1-benzyl-5- dialkylamino-1H-pyrrole-2,4-dicarboxylate derivatives

Optimization details and limitations of a novel synthetic method of 4-tert-butyl 2-ethyl 3-amino-1-benzyl-5-dialkylamino-1H-pyrrole-2,4- dicarboxylate derivatives are herein disclosed. This synthesis consists of four steps that include a highly selective cyclization, and can be carried out from starting materials to target compounds without column chromatography purification. The high selectivity is controlled by lithium coordination and steric hindrance caused by tert-butyl ester.