1169834-47-2Relevant academic research and scientific papers
Concise total synthesis of (±)-aspidospermidine via an oxidative Hosomi-Sakurai process
Sabot, Cyrille,Guerard, Kimiaka C.,Canesi, Sylvain
, p. 2941 - 2943 (2009)
A concise total synthesis of (±)-aspidospermidine has been achieved in twelve steps from inexpensive 4-ethylphenol, based on an oxidative Hosomi-Sakurai reaction via the concept of "aromatic ring umpolung".
'Aromatic ring umpolung', a rapid access to the main core of several natural products
Guérard, Kimiaka C.,Sabot, Cyrille,Beaulieu, Marc-André,Giroux, Marc-André,Canesi, Sylvain
scheme or table, p. 5893 - 5901 (2010/09/09)
Treatment of various substituted phenols in the presence of (diacetoxyiodo)benzene promotes the formation of a phenoxenium ion, a very electrophilic species able to react with various nucleophiles leading rapidly to a plethora of different cores present i
