1169845-29-7Relevant academic research and scientific papers
Synthesis of substituted pyrrolin-4-ones from amino acids in mild conditions via a gold-catalyzed approach
Gouault, Nicolas,Le Roch, Myriam,Cornee, Carole,David, Michele,Uriac, Philippe
scheme or table, p. 5614 - 5617 (2009/12/08)
(Chemical Equation Presented) The gold-catalyzed cyclization of various α-amino-ynone derivatives gave the corresponding pyrrolin-4-ones in high yields. Moreover, the use of gold(III) oxide as catalyst allows a moderate to total stereocontrol during the cyclization. These pyrrolin-4-ones are highly useful intermediates for the synthesis of functionalized pyrrolidines and other natural products.
