1169874-46-7Relevant academic research and scientific papers
Synthesis of polysubstituted 1,2-dihydroisoquinolines via a CuI-catalyzed arylation/condensation cascade process
Wu, Yangyang,Zhang, Yihua,Jiang, Yongwen,Ma, Dawei
experimental part, p. 3683 - 3685 (2009/10/04)
CuI-catalyzed reaction of 1-(2-bromophenyl)-propargylamines 4 with β-keto esters in i-PrOH/H2O (3:1) at 50 °C provides polysubstituted 1,2-dihydroisoquinolines. The transformation involves a cascade intermolecular C-C bond formation and intramo
