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• 126-81-8 dimedone 
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Relevant academic research and scientific papers

Synthesis, characterization and application of nano-CoAl2O4 as an efficient catalyst in the preparation of hexahydroquinolines

In this work, nano-CoAl2O4 was prepared and characterized by FT-IR, energy dispersive X-ray analysis (EDX), X-ray diffraction patterns (XRD), scanning electron microscopy (SEM), vibrating sample magnetometer (VSM) and transmission el

Chitosan: a sustainable, reusable and biodegradable organocatalyst for green synthesis of 1,4-dihydropyridine derivatives under solvent-free condition

Abstract: Chitosan, a biodegradable green catalyst, was found to be an impressive system for one-pot four-component reaction of different aldehydes, dimedone, β‐ketoesters or acetoacetanilide, and ammonium acetate leading to 1,4-dihydropyridine derivatives via Hantzsch-type condensation under solvent-free condition. This methodology produces diverse superiorities such as operational simplicity, short reaction time, satisfied yield and recyclable catalyst. In this work, we attempted to develop several modifications for the classical Hantzsch conversion to report a novel eco-friendly method that is free from previously reported disadvantages. Graphical Abstract: [Figure not available: see fulltext.]

High density sulfonated magnetic carbon quantum dots as a photo enhanced, photo-induced proton generation, and photo switchable solid acid catalyst for room temperature one-pot reaction

The preparation of photo enhanced and switchable (on/off mode) sulfonated magnetic carbon quantum dots was investigated in the present work. First, the as-synthesized carbon quantum dots (CQDs) were easily separated using a magnet (instead of using a dial

Catalyst-free, Knoevenagel-Michael addition reaction of dimedone under microwave irradiation: An efficient one-pot synthesis of polyhydroquinoline derivatives

Present investigation reports a concise and efficient protocol for the synthesis of polyhydroquinoline derivatives through coupling of four different components viz. aromatic aldehydes, dimedone, ethyl acetoacetate or ethyl cyanoacetate, and ammonium acetate. The same phenomenon can be observed using arylmethylene bis(3-hydroxy-2-cyclohexene-1-ones), ethyl acetoacetate, and ammonium acetate in one pot under microwave irradiation. The key advantages of the given protocol include short reaction time, high yields, and simple work-up and purification procedure. The present method also allows us to synthesize highly functionalized title compounds from simple and readily available starting materials.

Preparation and characterization of Cu (II) supported on poly(8-hydroxyquinoline-p-styrene sulphonate) and its application as catalyst for the synthesis of hexahydroquinolines

Cu (II) supported on poly(8-hydroxyquinoline-p-styrenesulfonate) (Cu (II)@PHQSS) was prepared and fully characterized by the different techniques including fourier transform infrared spectroscopy (FT-IR), 1H NMR, 13C NMR, thermal gra

Sulfonamide-functionalized covalent organic framework (COF-SO3H): an efficient heterogeneous acidic catalyst for the one-pot preparation of polyhydroquinoline and 1,4-dihydropyridine derivatives

Herein, we report the sulfonamide-functionalized covalent organic framework (COF-SO3H) prepared from melamine and terephthalaldehyde and subsequent sulfonation, as an acidic porous catalyst for the one-pot preparation of polyhydroquinoline and

Application of salicylic acid as an eco-friendly and efficient catalyst for the synthesis of 2,4,6-triaryl pyridine, 2-amino-3-cyanopyridine, and polyhydroquinoline derivatives

In this study, three eco-friendly, efficient, and convenient protocols have been reported for one-pot synthesis of 2,4,6-triaryl pyridine, 2-amino-3-cyanopyridine, and polyhydroquinoline derivatives using salicylic acid as a catalyst under solvent-free condition. The reported protocols offer several significant advantages such as the application of a nontoxic, neutral, and cheap catalyst, environmentally friendly conditions, the easy isolation of products by filtering, short reaction times, simple methodology, and good yields.

Synthesis of sulfonated melamine-functionalized Fe3O4@SiO2@Si–(CH2)3@melamine nanoparticles and its application in the synthesis of 4,4’-(aryl methylene)bis(3-methyl-1H-pyrazol-5-ol)s and hexahydroqui

In this work, sulfonated melamine-functionalized Fe3O4@SiO2@Si-(CH2)3@melamine nanoparticles were prepared through a simple approach and characterized by energy dispersive X-ray analysis (EDX), field

Identification of dihydropyridines that reduce cellular tau levels

A series of dihydropyridines were identified that have an effect on the accumulation of tau, an important target in Alzheimer's disease. The dihydropyridine collection was expanded using the Hantzsch multicomponent reaction to develop preliminary structur

Palladium(0) nanoparticles: An efficient catalyst for the one-pot synthesis of polyhydroquinolines

A mild, concise, and efficient protocol for the synthesis of polyhydroquinoline via four component reaction of aromatic aldehydes, dimedone, ethyl acetoacetate or ethyl cyanoacetate, and ammonium acetate using Pd-nanoparticles is described. The same phenomenon was observed in the case of arylmethylene bis(3-hydroxy-2-cyclohexene-1-ones), ethyl acetoacetate, ammonium acetate, and Pd-nanoparticles in one-pot. The present method also allows us to synthesize highly functionalized title compounds from simple and readily available inputs.