117016-15-6 Usage
Description
7-O-(3-amino-2,3,6-trideoxy-alpha-hexopyranosyl)-epsilon-isorhodomycinone is an anthracycline derivative, specifically an aklavinone, with a 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl residue attached at position 4 via a glycosidic linkage. 7-O-(3-amino-2,3,6-trideoxy-alpha-hexopyranosyl)-epsilon-isorhodomycinone is characterized by its unique chemical structure and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
7-O-(3-amino-2,3,6-trideoxy-alpha-hexopyranosyl)-epsilon-isorhodomycinone is used as a pharmaceutical compound for its potential therapeutic properties. The compound's unique structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs.
Used in Anticancer Applications:
In the field of oncology, 7-O-(3-amino-2,3,6-trideoxy-alpha-hexopyranosyl)-epsilon-isorhodomycinone is used as an anticancer agent. Its anthracycline nature suggests that it may have similar mechanisms of action to other anthracyclines, which are known for their ability to intercalate DNA, inhibit topoisomerase II, and generate free radicals, leading to the inhibition of tumor growth and progression.
Used in Drug Delivery Systems:
Similar to gallotannin, 7-O-(3-amino-2,3,6-trideoxy-alpha-hexopyranosyl)-epsilon-isorhodomycinone may also benefit from novel drug delivery systems to enhance its applications and efficacy against cancer cells. The development of organic and metallic nanoparticles as carriers for this compound could improve its delivery, bioavailability, and therapeutic outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 117016-15-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,0,1 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 117016-15:
(8*1)+(7*1)+(6*7)+(5*0)+(4*1)+(3*6)+(2*1)+(1*5)=86
86 % 10 = 6
So 117016-15-6 is a valid CAS Registry Number.
InChI:InChI=1/C28H31NO12/c1-4-28(38)8-13(41-14-7-10(29)22(32)9(2)40-14)17-18(21(28)27(37)39-3)26(36)20-19(25(17)35)23(33)15-11(30)5-6-12(31)16(15)24(20)34/h5-6,9-10,13-14,21-22,30-32,35-36,38H,4,7-8,29H2,1-3H3/t9-,10-,13-,14-,21-,22+,28+/m0/s1
117016-15-6Relevant articles and documents
Semisynthetic ε-(iso)rhodomycins: a new glycosylation variant and modification reactions
Kolar, Cenek,Kneissl, Guenther,Knoedler, Ursula,Dehmel, Konrad
, p. 89 - 100 (2007/10/02)
Synthesis of 7-O-(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)-ε-(iso)rhodomycinones 16 and 17, and their 3'-morpholino derivatives are described.Glycosylation (trimethylsilyl triflate, 10:1 dichloromethane-acetone, -35 deg C) of 1-O-tert-butyldimethyls
