117019-69-9Relevant academic research and scientific papers
Acid-catalysed Rearrangements of Steroid Alkenes. Part 2. A Re-investigation of the Backbone Rearrangement of Cholest-5-ene
Peakman, Torren M.,Ellis, Karen,Maxwell, James R.
, p. 1071 - 1076 (2007/10/02)
Backbone rearrangement of cholest-5-ene (1) with boron trifluoride-diethyl ether gives, in addition to the well known diacholest-13(17)-enes (4a,b), their 10β counterparts (6a,b) as minor products.With anhydrous toluene-p-sulphonic acid-acetic acid, additional products include components also isomeric at C-10 and C-20 and having a spiro C/D ring junction.A proposed scheme for the rearrangement is given.
