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1170321-78-4

1170321-78-4

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  • 3-(benzenesulfonyl)-n-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide

    Cas No: 1170321-78-4

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1170321-78-4 Usage

Uses

3-(Phenylsulfonyl)-N-(4-(trifluoromethyl)phenyl)-8-azabicyclo[3.2.1]octane-8-carboxamide is an inhibitor of long chain fatty acid elongase 6 (ELOVL6).

Check Digit Verification of cas no

The CAS Registry Mumber 1170321-78-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,0,3,2 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1170321-78:
(9*1)+(8*1)+(7*7)+(6*0)+(5*3)+(4*2)+(3*1)+(2*7)+(1*8)=114
114 % 10 = 4
So 1170321-78-4 is a valid CAS Registry Number.

1170321-78-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(benzenesulfonyl)-N-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:1170321-78-4 SDS

1170321-78-4Synthetic route

3-endo-(phenylsulfonyl)-8-azabicyclo[3.2.1]octane hydrogenchloride
1170321-46-6

3-endo-(phenylsulfonyl)-8-azabicyclo[3.2.1]octane hydrogenchloride

phenyl N-[4-(trifluoromethyl)-phenyl]carbamate
23779-14-8

phenyl N-[4-(trifluoromethyl)-phenyl]carbamate

3-endo-(phenylsulfonyl)-N-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide
1170321-78-4

3-endo-(phenylsulfonyl)-N-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide

Conditions
ConditionsYield
With triethylamine In chloroform at 80℃; for 1h;91%

1170321-78-4Downstream Products

1170321-78-4Relevant articles and documents

Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2. 1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors

Nagase, Tsuyoshi,Takahashi, Toshiyuki,Sasaki, Takahide,Nagumo, Akira,Shimamura, Ken,Miyamoto, Yasuhisa,Kitazawa, Hidefumi,Kanesaka, Maki,Yoshimoto, Ryo,Aragane, Katsumi,Tokita, Shigeru,Sato, Nagaaki

supporting information; experimental part, p. 4111 - 4114 (2010/02/17)

Long chain fatty acid elongase 6 (ELOVL6) catalyzes the elongation of long chain fatty acyl-CoAs and is a potential target for the treatment of metabolic disorders. The ultrahigh throughput screen of our corporate chemical collections resulted in the iden

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