117082-62-9

Basic information

• Product Name: N-(3-methoxy-2-nitrobenzoyl)-L-prolinol
• Synonyms: N-(3-methoxy-2-nitrobenzoyl)-L-prolinol
• CAS NO: 117082-62-9
• Molecular Weight: 280.28
• Mol File: 117082-62-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-methoxy-2-nitrobenzoyl)-L-prolinol(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-methoxy-2-nitrobenzoyl)-L-prolinol(117082-62-9)
• EPA Substance Registry System: N-(3-methoxy-2-nitrobenzoyl)-L-prolinol(117082-62-9)

Safety Data

• Hazardous Substances Data: 117082-62-9(Hazardous Substances Data)

Upstream product

• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 4920-80-3 3-methoxy-2-nitrobenzoic acid 
• 117082-61-8 N-(3-methoxy-2-nitrobenzoyl)-L-proline methyl ester 

Downstream Products

• 117082-63-0 N-(3-methoxy-2-nitrobenzoyl)-L-prolinal dimethyl acetal 
• 110562-21-5 N-(-3-methoxy-2-aminobenzoyl)-L-prolinal dimethyl acetal 
• 117143-70-1 N-(3-methoxy-2-nitrobenzoyl)-L-prolinal 

Relevant articles and documents

New methods and reagents in organic synthesis. 92. A stereoselective synthesis of tilivalline and its analogs

Tilivalline (1a), a metabolite from Klebsiella pneumoniae var. oxytoca, and its derivatives 1 have been efficiently and stereoselectively synthesized from diphenyl phosphorazidate, the 2-oxazoline 2, the L-proline derivatives 5, and indole; the key step is a Mannich type intramolecular cyclization accompanied with completely stereoselective introduction of indole. Furthermore, 11-substituted 5H- pyrrolo[2,1-c][1,4]benzodiazepin-5-ones (16) have been also synthesized from the acetal amide 9a and various nucleophiles by the use of this new Mannich type cyclization.