1170856-93-5

Basic information

• Product Name: Calcein tetraethyl ester
• Synonyms: Calcein tetraethyl ester;N,N'-[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-4',5'-diyl)bis(methylene)]bis[N-(2-ethoxy-2-oxoethyl)-glycine] 1,1'-diethyl ester;Tetraethyl 2,2',2'',2'''-(((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-4',5'-diyl)bis(methylene))bis(azanetriyl))tetraacetate
• CAS NO: 1170856-93-5
• Molecular Formula: C38H42N2O13
• Molecular Weight: 734.74568
• Mol File: 1170856-93-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Acetonitrile (Slightly), Methanol (Slightly, Heated)
• CAS DataBase Reference: Calcein tetraethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Calcein tetraethyl ester(1170856-93-5)
• EPA Substance Registry System: Calcein tetraethyl ester(1170856-93-5)

Safety Data

• Hazardous Substances Data: 1170856-93-5(Hazardous Substances Data)

Usage

Uses

Tetraethyl Fluorescein Bis(methylene)bis(azanetriyl)tetraacetate is an intermediate used in the synthesis of Calcein AM (C125400), which is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.