117106-19-1 Usage
Description
Z-N-ME-SER(TBU)-OH DCHA is a serine derivative chemical compound featuring a tert-butyl ester on the amino group. Z-N-ME-SER(TBU)-OH DCHA is integral in peptide synthesis, acting as a building block for the construction of intricate peptide structures. The tert-butyl ester group shields the amino group of the serine, facilitating selective deprotection and further molecular manipulation in organic synthesis. Its design also enhances the stability and ease of handling of the serine derivative, establishing it as a vital component in chemical and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
Z-N-ME-SER(TBU)-OH DCHA is used as a building block for the synthesis of complex peptides, contributing to the development of novel pharmaceutical compounds. Z-N-ME-SER(TBU)-OH DCHA's protective tert-butyl ester group allows for selective deprotection and precise molecular manipulation, which is crucial for creating specific peptide sequences with targeted therapeutic effects.
Used in Chemical Research:
In the field of chemical research, Z-N-ME-SER(TBU)-OH DCHA is utilized as a key component in the synthesis of various organic compounds. Its stability and ease of handling, due to the protective tert-butyl ester, make it an essential tool for conducting controlled organic reactions and exploring new chemical pathways.
Used in Peptide Synthesis:
Z-N-ME-SER(TBU)-OH DCHA is used as a serine derivative in the creation of peptide structures. Its role in peptide synthesis is to provide a stable and protected amino acid building block that can be selectively deprotected and further manipulated to achieve the desired peptide sequence, which is vital for the development of new bioactive peptides with specific functions in medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 117106-19-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,1,0 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 117106-19:
(8*1)+(7*1)+(6*7)+(5*1)+(4*0)+(3*6)+(2*1)+(1*9)=91
91 % 10 = 1
So 117106-19-1 is a valid CAS Registry Number.
117106-19-1Relevant articles and documents
Biosynthesis of Hyalodendrin and Didethiobis(methylthio)hyalodendrin, Sulphur-containing 2,5-Dioxopiperazines of the 3S,6S Series
Boente, Maria I. Pita,Kirby, Gordon W.,Patrick, Graham L.,Robins, David J.
, p. 1283 - 1290 (2007/10/02)
cyclo-(L-Phe-L-Ser) 8, a known biosynthetic precursor of the (3R,6R)-epidithiodioxopiperazine gliotoxin 4, was efficiently incorporated (42percent), in Hyalodendron sp. (FSC-601) cultures, into the 3S,6S metabolite didethiobis(methylthio)hyalodendrin (DBH) 7 without significant change in the 3H:14C ratio.None of the three diasteromers of cyclo-(L-Phe-L-Ser) was incorporated into DBH to any significant extent.The 13C label from cyclo-(L-Phe-L-Ser) was located, in the expected site, in DBH by 13C NMR spectroscopy.Gliotoxin derived in Gliocladium virens from the doubly labelled precursor 8 was degraded to locate, in similar manner, the 14C label.The N-methyl derivative 16 of cyclo-(L-Phe-L-Ser) was not incorporated detectably into either gliotoxin or DBH.Radioactivity from the doubly labelled, linear dipeptides 17 and 18, possible precursors for the cyclodipeptide 8, was incorporated with moderate efficiency into gliotoxin.However, the 3H:14C ratios for the dipeptides and the derived gliotoxin differd substantially, indicating that the peptides had undergone cleavage in the fungus before incorporation.
