1171124-66-5

Basic information

• Product Name: ethyl 5-chloro-4-ethyl-1H-iMidazole-2-carboxylate
• Synonyms: ethyl 5-chloro-4-ethyl-1H-iMidazole-2-carboxylate
• CAS NO: 1171124-66-5
• Molecular Formula: C8H11ClN2O2
• Molecular Weight: 202.63814
• Mol File: 1171124-66-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 329.7±34.0 °C(Predicted)
• Appearance: /
• Density: 1.265±0.06 g/cm3(Predicted)
• PKA: 9.49±0.10(Predicted)
• CAS DataBase Reference: ethyl 5-chloro-4-ethyl-1H-iMidazole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-chloro-4-ethyl-1H-iMidazole-2-carboxylate(1171124-66-5)
• EPA Substance Registry System: ethyl 5-chloro-4-ethyl-1H-iMidazole-2-carboxylate(1171124-66-5)

Safety Data

• Hazardous Substances Data: 1171124-66-5(Hazardous Substances Data)

Upstream product

• 1171124-65-4 ethyl 5-ethyl-1H-imidazole-2-carboxylate 

Downstream Products

• 1171124-67-6 4-chloro-5-ethyl-1H-imidazole-2-carboxylic acid 

Relevant articles and documents

IMIDAZOLE CARBONYL COMPOUND

To develop an antibiotic having a novel mechanism of action, the present inventors have searched for a compound that has weak cytotoxicity, the physical property of high solubility in water, the effect of inhibiting both DNA gyrase GyrB and topoisomerase IV ParE subunits, and sufficient antibacterial activity. As a result, the present inventors have completed the present invention by finding that a compound of the present invention represented by the general formula (1), a pharmacologically acceptable salt thereof, and a prodrug thereof have desirable properties. The present invention provides a pharmaceutical composition (particularly, a preventive or therapeutic composition for infectious disease) comprising a compound represented by the formula (1), a pharmacologically acceptable salt thereof, or a prodrug thereof as an active ingredient.