1171130-67-8 Usage
General Description
(3-DiMethylaMinoMethylene-4-oxo-cyclohexyl)-carbaMic acid tert-butyl ester, also known as DMACCA, is a chemical compound with the molecular formula C12H21NO3. It is a carbamate derivative that is commonly used in organic synthesis and medicinal chemistry. DMACCA is known for its potential application as a reactant in the synthesis of various pharmaceutical compounds. It is typically used as a reagent in chemical reactions due to its ability to undergo specific transformations, making it a valuable tool in the production of complex organic molecules. The tert-butyl ester group in DMACCA makes it a versatile and stable compound that is suitable for use in a wide range of chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1171130-67-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,1,1,3 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1171130-67:
(9*1)+(8*1)+(7*7)+(6*1)+(5*1)+(4*3)+(3*0)+(2*6)+(1*7)=108
108 % 10 = 8
So 1171130-67-8 is a valid CAS Registry Number.
1171130-67-8Relevant articles and documents
Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis
Gomez, Laurent,Hack, Michael D.,Wu, Jiejun,Wiener, John J.M.,Venkatesan, Hari,Santillan Jr., Alejandro,Pippel, Daniel J.,Mani, Neelakandha,Morrow, Brian J.,Motley, S. Timothy,Shaw, Karen Joy,Wolin, Ronald,Grice, Cheryl A.,Jones, Todd K.
, p. 2723 - 2727 (2007)
In an attempt to search for a new class of antibacterial agents, we have discovered a series of pyrazole analogs that possess good antibacterial activity for Gram-positive and Gram-negative organisms via inhibition of type II bacterial topoisomerases. We have investigated the structure-activity relationships of this series, with an emphasis on the length and conformation of the linker. This work led to the identification of tetrahydroindazole analogs, such as compound 1, as the most potent class of compounds.
