1171245-84-3

Upstream product

• 1171245-81-0 N-ethyl-N-hex-5-yn-1-yl-2-[2-(TBS)oxyethyl]-4,4-diphenyl-4H-1,3-benzodioxin-6-amine 

Downstream Products

• 1171245-87-6 2-{6-[ethyl(hex-5-yn-1-yl)amino]-4,4-diphenyl-4H-1,3-benzodioxin-2-yl}ethyl-N,N-bis(2-chloroethyl)amidochlorophosphate 

Relevant academic research and scientific papers

PHOTO-ACTIVATABLE THERAPEUTIC AGENTS AND METHODS OF USING

Novel photo-activatable pro-therapeutic agents and methods for their synthesis and use are described. The photo-activatable pro-therapeutic agents are inactive pro-forms of compounds that can be activated in situ, for example, by providing a pro-therapeutic agent to a subject and photo-activating the pro-therapeutic agent at a selected area of the subject. Also disclosed are methods for administering the photo-activatable pro-therapeutic agents to a subject then activating the pro-therapeutic agents at a selected area of the subject by exposing that area to light.

Photolabile carbonyl protecting group: A new tool for light-controlled release of anticancer agents

A new type of photolabile carbonyl-protecting group was utilized in releasing anticancer agents upon irradiation at 350 nm in an aqueous environment.