1171310-24-9Relevant academic research and scientific papers
NbCl5 a multifunctional reagent for the synthesis of new halogenated aminoquinoline compounds through innovative one-pot reaction and the acidochromism effect
dos Santos, Giovanny Carvalho,Moreno, Vitor Fernandes,Oshiro, Paula Beatriz,da Silva-Filho, Luiz Carlos
, p. 6144 - 6149 (2018)
This paper describes an original one-pot way to synthesize nine new halogenated aminoquinoline derivatives using reactions conducted by niobium pentachloride. Subsequently, we describe an efficient and selective reduction reaction of nitroquinolines using niobium pentachloride and zinc, producing important compounds in the organic synthesis. The results showed that it is an important tool to synthesize these compounds, besides being time- and resources-saving and generating good yields. A quick study of acidochromism was performed.
Facile Synthesis and Photophysical Characterization of New Quinoline Dyes
Santos, Giovanny Carvalho dos,de Andrade Bartolomeu, Aloisio,Ximenes, Valdecir Farias,da Silva-Filho, Luiz Carlos
, p. 271 - 280 (2017/02/05)
This paper describes the synthesis of new quinoline derivatives, molecules that has been long interest in the organic and medicinal chemistry. Through the Multicomponent Reaction (MCR), an important tool in modern synthetic methodology, that generate products with good structural complexity, in addition to economy of atoms and selectivity, we provide easy access to the preparation of quinoline derivatives. The reactions were promoted by niobium pentachloride, as a Lewis acid. Subsequently, the synthesis of new aminoquinoline derivatives with good yields was performed using Pd/C and hydrazine. The photophysical investigations of quinoline derivatives show the substituent effect on the optical properties characterization was done by absorption and photoluminescence measurements with quantum yields of up to 83?%, the presence of the amino group at position 6 at the quinoline backbone was crucial for obtaining these increased quantum yields. Results show that these molecules may have potential use for a variety of applications and mainly attracts attention because of its wide potential of applicability in optoelectronic devices.
Microwave promoted one-pot preparation of fluorinated propargylamines and their chemical transformation
Chen, Xiao-Lei,Zhang, Jian-Min,Shang, Wen-Li,Lu, Bei-Qiong,Jin, Jian-An
experimental part, p. 139 - 145 (2012/03/26)
A series of fluorinated propargylamines have been synthesized from the one-pot three-component reaction of fluorobenzaldehyde, aniline and phenylacetylene under solvent-free and microwave irradiation. The fluorinated propargylamines were then further transformed to chalcones or quinoline derivatives respectively depending on the different structures of propargylamines.
