117170-33-9Relevant academic research and scientific papers
Aryl- and Alkynyltri-isopropoxytitanium Reagents in Regioselective Carbon-Carbon Bond Formation in Azines
Gundersen, Lise-Lotte,Rise, Frode,Undheim, Kjell
, p. 5647 - 5656 (2007/10/02)
Regioselective arylation in the 4-position in pyridines results from 1:1-adduct formation between an aryltriisopropoxytitanium reagent and N-isobutyloxycarbonyl- or an N-silyloxymethyl-3-cyanopyridinium salt after successive DDQ dehydrogenation and cleavage of the 1-substituent.Complete regioselectivity for new C-C bond formation in the 4-position results in the adduct formation between aryl- and phenylethynyltri-isopropoxytitanium reagents and pyrimidin-2(1H)-ones; with ethynyltriisopropoxytitanium the new C-C bond formation occurs at the 6-position.
Ethynyltriisopropoxytitanium reactions with pyrimidinones
Rise, Frode,Grace, David,Undheim, Kjell
, p. 341 - 346 (2007/10/02)
Ethynyltriisopropoxytitanium has beem generated in situ from ethynyllithium and chlorotriisopropoxytitanium at -80 deg C.It forms 1/1 adducts with pyrimidin-2(1H)-ones with exclusive carbon-carbon bond formation at C(6).The products after quenching ethyny
