117174-87-5 Usage
General Description
1-(2,4,5-TRIMETHYLPHENYL)-2-THIOUREA is a chemical compound with the molecular formula C10H14N2S. It is a thiourea derivative that contains a phenyl group with three methyl substituents and a thiourea functional group. 1-(2,4,5-TRIMETHYLPHENYL)-2-THIOUREA has been studied for its potential pharmaceutical and biological properties, including its antifungal and antibacterial activities. It is also used as a building block in organic synthesis to create more complex molecules. Additionally, 1-(2,4,5-TRIMETHYLPHENYL)-2-THIOUREA has been investigated for its potential applications in materials science, such as in the development of novel polymers and composite materials. Overall, this compound has garnered interest for its varied potential uses in medicine, chemistry, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 117174-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,1,7 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 117174-87:
(8*1)+(7*1)+(6*7)+(5*1)+(4*7)+(3*4)+(2*8)+(1*7)=125
125 % 10 = 5
So 117174-87-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2S/c1-6-4-8(3)9(5-7(6)2)12-10(11)13/h4-5H,1-3H3,(H3,11,12,13)
117174-87-5Relevant articles and documents
Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors
Wilson, Kenneth J.,Illig, Carl R.,Subasinghe, Nalin,Hoffman, James B.,Jonathan Rudolph,Soll, Richard,Molloy, Christopher J.,Bone, Roger,Green, David,Randall, Troy,Zhang, Marie,Lewandowski, Frank A.,Zhou, Zhao,Sharp, Celia,Maguire, Diane,Grasberger, Bruce,DesJarlais, Renee L.,Spurlino, John
, p. 915 - 918 (2007/10/03)
The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is described. Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities.
