117174-87-5 Usage
Uses
Used in Pharmaceutical Applications:
1-(2,4,5-TRIMETHYLPHENYL)-2-THIOUREA is used as an active pharmaceutical ingredient for its antifungal and antibacterial properties, offering potential treatments for various infections caused by fungi and bacteria.
Used in Organic Synthesis:
1-(2,4,5-TRIMETHYLPHENYL)-2-THIOUREA is used as a building block in organic synthesis for constructing more complex molecules, contributing to the development of new chemical entities with potential applications in various fields.
Used in Materials Science:
1-(2,4,5-TRIMETHYLPHENYL)-2-THIOUREA is used as a component in the development of novel polymers and composite materials, potentially enhancing the properties of these materials for specific applications in various industries.
Used in Chemical Research:
1-(2,4,5-TRIMETHYLPHENYL)-2-THIOUREA is used as a subject of study in chemical research to explore its properties and potential applications, contributing to the advancement of knowledge in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 117174-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,1,7 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 117174-87:
(8*1)+(7*1)+(6*7)+(5*1)+(4*7)+(3*4)+(2*8)+(1*7)=125
125 % 10 = 5
So 117174-87-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2S/c1-6-4-8(3)9(5-7(6)2)12-10(11)13/h4-5H,1-3H3,(H3,11,12,13)
117174-87-5Relevant academic research and scientific papers
Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors
Wilson, Kenneth J.,Illig, Carl R.,Subasinghe, Nalin,Hoffman, James B.,Jonathan Rudolph,Soll, Richard,Molloy, Christopher J.,Bone, Roger,Green, David,Randall, Troy,Zhang, Marie,Lewandowski, Frank A.,Zhou, Zhao,Sharp, Celia,Maguire, Diane,Grasberger, Bruce,DesJarlais, Renee L.,Spurlino, John
, p. 915 - 918 (2007/10/03)
The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is described. Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities.
Improved Procedures for the Preparation of Cycloalkyl-, Arylalkyl-, and Arylthioureas
Rasmussen, C. R.,Villani, F. J.,Weaner, L. E.,Reynolds, B. E.,Hood, A. R.,et al.
, p. 456 - 459 (2007/10/02)
An improved procedure for the preparation of arylthioureas consists of the reaction of benzoyl isothiocyanate with anilines in acetone and debenzoylation of the resultant N-aryl-N'-benzoylthioureas with 5percent aqueous sodium hydroxide.Bicycloalkylthioureas and N-(arylalkyl)thioureas (e.g. 9H-9-fluorenylthiourea) are directly prepared from the corresponding isothiocyanates and ammonia.
