1171816-83-3Relevant academic research and scientific papers
Asymmetric approach to hyacinthacines B1 and B2
Reddy, Paidi Venkatram,Smith, Julien,Kamath, Anushree,Jamet, Hélène,Veyron, Ama?l,Koos, Peter,Philouze, Christian,Greene, Andrew E.,Delair, Philippe
, p. 4840 - 4849 (2013/07/05)
Naturally occurring hyacinthacines B1 and B2 have been prepared from a common, easily available, advanced intermediate. The approach features several highly stereoselective transformations: inter alia, a dichloroketene-enol ether [2 + 2] cycloaddition, a Bruylants alkylation, and an amino-nitrile alkylation-reduction.
Nonchiral-pool synthesis of (+)-hyacinthacine B1
Reddy, Paidi Venkatram,Koos, Peter,Veyron, Ama?l,Greene, Andrew E.,Delair, Philippe
body text, p. 1141 - 1143 (2009/10/10)
The first nonchiral-pool total synthesis of (+)-hyacinthacine B1 has been achieved. The synthesis uses as key steps an efficient [2+2] cycloaddition of dichloroketene to a chiral enol ether, two diastereoselective Bruylants-like alkylations, an
