117196-08-4

Basic information

• Product Name: 2,4-Dibromopyridine-1-oxide
• Synonyms: 2,4-Dibromopyridine-1-oxide;2,4-Dibromopyridine-N-oxide;Pyridine, 2,4-dibroMo-,1-oxide;2,4-dibromo-,1-oxide
• CAS NO: 117196-08-4
• Molecular Formula: C₅H₃Br₂NO
• Molecular Weight: 252.89
• Mol File: 117196-08-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 95℃
• Boiling Point: 387.1 °C at 760 mmHg
• Flash Point: 187.9 °C
• Appearance: /
• Density: 2.15±0.1 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 7.55E-06mmHg at 25°C
• Refractive Index: 1.652
• PKA: -0.86±0.10(Predicted)
• CAS DataBase Reference: 2,4-Dibromopyridine-1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dibromopyridine-1-oxide(117196-08-4)
• EPA Substance Registry System: 2,4-Dibromopyridine-1-oxide(117196-08-4)

Safety Data

• Hazardous Substances Data: 117196-08-4(Hazardous Substances Data)

Usage

General Description

2,4-Dibromopyridine-1-oxide is a chemical compound with the molecular formula C5H3Br2NO. It is a yellow to orange crystalline powder that is insoluble in water but soluble in organic solvents. This chemical is primarily used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as an intermediate in the manufacturing of other organic compounds. 2,4-Dibromopyridine-1-oxide is considered to be toxic if ingested or inhaled and is a skin and eye irritant. It should be handled and stored with caution and proper protective equipment.

InChI:InChI=1/C5H3Br2NO/c6-4-1-2-8(9)5(7)3-4/h1-3H

Upstream product

• 52092-43-0 2-bromo-4-nitropyridine N-oxide 

Downstream Products

• 58530-53-3 2,4-dibromopyridine 

Relevant articles and documents

Synthesis of 2,4-dibromopyridine and 4,4'-dibromo-2,2'-bipyridine. Efficient usage in selective bromine-substitution under palladium-catalysis

We report an efficient method for preparing 2,4-dibromopyridine and 4,4'-dibromo-2,2'-bipyridine from the corresponding nitroazine N-oxide in one step via a tandem nucleophilic substitution-N-oxide reduction process. The one step preparation of 4,4'-dihalo-2,2'-bipyridines from dihalopyridines via a Stille reaction is also described. 4,4'-Dibromo-2,2'-bipyridine undergoes selective mono- or disubstitution processes under palladium catalysis. This short synthetic procedure is an efficient and reliable process for preparing conjugated pyridine and 2,2'-bipyridine building blocks for applications in coordination chemistry and materials science.