117196-96-0Relevant articles and documents
N-(Indol-3-ylglyoxylyl)methionine derivatives: preparation and gastric anti-secretory activity
Settimo, Antonio da,Primofiore, Giampaolo,Marini, Anna Maria,Ferrarini, Pier Luigi,Franzone, Jose Sebastian,et al.
, p. 21 - 24 (2007/10/02)
The authors describe the synthesis of several N-(indol-3-ylglyoxylyl)methionine derivatives.The target compounds were prepared starting from substituted indoleglyoxylyl chlorides and methionine ethyl ester.Some of them were tested for their anti-secretory activity.Among these compounds, the N-(5-chloroindol-3-ylglyoxylyl)methionine Vc was the most active, being quite comparable to cimetidine.Keywords - methionine / indoles / gastric anti-secretory activity.