117197-09-8Relevant articles and documents
SYNTHESIS OF 20-IODOEICOSANOIK AND 20--IODOEICOSANOIK ACIDS
Protiva, Jiri,Pecka, Jaroslav,Urban, Jiri,Zima, Jiri
, p. 1546 - 1554 (2007/10/02)
20-Iodoeicosanoic acid (X) was prepared in 9 steps, its carbon cain being constructed from thiophene and ethyl ester chlorides of dodecanedioic and butanedioic acids.Isotope exchange afforded 20--iodoeicosanoic acid required for scintigraphic studies of the myocardium.Desulfuration of the thiophene precursor VIII was accompanied by formation of side products XI-XIX arising by cleavage of the thiophene C-C bonds.Desulfuration of the model compounds XX and XXI has shown that the formation of these products is general.