1172067-95-6

Basic information

• Product Name: 5-Bromo-4-fluoro-7-azaind...
• Synonyms: 5-Bromo-4-fluoro-7-azaind...;5-BroMo-4-fluoro-7-azaindole;5-broMo-4-fluoro-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 5-broMo-4-fluoro-
• CAS NO: 1172067-95-6
• Molecular Formula: C₇H₄BrFN₂
• Molecular Weight: 215.03
• Mol File: 1172067-95-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 277.9±40.0 °C(Predicted)
• Appearance: /
• Density: 1.90±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.00±0.20(Predicted)
• CAS DataBase Reference: 5-Bromo-4-fluoro-7-azaind...(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-4-fluoro-7-azaind...(1172067-95-6)
• EPA Substance Registry System: 5-Bromo-4-fluoro-7-azaind...(1172067-95-6)

Safety Data

• Hazardous Substances Data: 1172067-95-6(Hazardous Substances Data)

Usage

General Description

5-Bromo-4-fluoro-7-azaindole is a chemical compound that is characterized by the presence of bromine, fluorine and a nitrogenous organic compound called azaindole. Its precise molecular formula is C7H4BrFN2. It is commonly used in scientific research, particularly in the pharmaceutical industry, for organic synthesis and drug design due to its unique physical and chemical properties. These involve being able to establish a variety of chemical bonds and interactions, which makes it an ideal building block in the synthesis of complex chemical structures. Analytical data including melting point, boiling point, flash point, density, refractive index, and solubility would be needed for proper chemical characterization. In terms of safety, proper handling and storage is important due to its potential reactivity to other substances.

Upstream product

• 640735-23-5 4-fluoro-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1172068-36-8 5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-ylamine 
• 1172067-98-9 5-bromo-4-fluoro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 1196508-42-5 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-methoxybenzamide trifluoroacetate 
• 1196505-03-9 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-chloro-4-fluorobenzamide hydrochloride 
• 1196504-51-4 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-fluorobenzamide hydrochloride 
• 1196504-67-2 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-methoxybenzamide hydrochloride 
• 1196504-40-1 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-methylbenzamide hydrochloride 
• 1196504-96-7 (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclobutanecarboxamide hydrochloride 
• 1196508-97-0 (R)-tert-butyl 1-(5-bromo-3-(3-chloro-4-fluorobenzamido)-1H-pyrrolo[2,3-b]pyridin-4-yl)piperidin-3-ylcarbamate 
• 1196508-54-9 (R)-tert-butyl 1-(5-bromo-3-(3-fluorobenzamido)-1H-pyrrolo[2,3-b]pyridin-4-yl)piperidin-3-ylcarbamate 
• 1196508-39-0 (R)-tert-butyl 1-(5-bromo-3-(3-methoxybenzamido)-1H-pyrrolo[2,3-b]pyridin-4-yl)piperidin-3-ylcarbamate 
• 1196507-83-1 (R)-tert-butyl 1-(5-bromo-3-(3-methylbenzamido)-1H-pyrrolo[2,3-b]pyridin-4-yl)piperidin-3-ylcarbamate 
• 1196508-96-9 N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-chloro-4-fluorobenzamide 
• 1196508-52-7 N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-fluorobenzamide 

Relevant articles and documents

KINASE ANTAGONISTS AND METHODS FOR MAKING AND USING THEM

Disclosed herein are small molecule compounds that are SGK1 antagonists, formulations and pharmaceutical compositions comprising the compounds, and methods of making and using them, for treating, ameliorating, preventing, reversing or slowing the progression of: a cancer, a tumor, a metastasis or a dysplastic or a dysfunctional cell condition responsive to inhibition of a kinase enzyme of the AGC group of kinases including SGK1, by administration of an AGC kinase inhibitor or antagonist.