1172114-50-9Relevant articles and documents
Application of combinatorial biocatalysis for a unique ring expansion of dihydroxymethylzearalenone
Rich, Joseph O.,Budde, Cheryl L.,McConeghey, Luke D.,Cotterill, Ian C.,Mozhaev, Vadim V.,Singh, Sheo B.,Goetz, Michael A.,Zhao, Annie,Michels, Peter C.,Khmelnitsky, Yuri L.
, p. 3059 - 3062 (2009)
Combinatorial biocatalysis was applied to generate a diverse set of dihydroxymethylzearalenone analogs with modified ring structure. In one representative chemoenzymatic reaction sequence, dihydroxymethylzearalenone was first subjected to a unique enzyme-