117240-14-9Relevant academic research and scientific papers
Synthesis, lipophilicity studies and antibacterial properties of some novel quaternary ammonium salts
Siatra-Papastaikoudi,Papadaki-Valiraki,Tsantili-Kakoulidou,Tzouvelekis,Mentis
, p. 392 - 394 (2007/10/02)
The synthesis of some novel quaternary ammonium salts, derivatives of 15- phenyl-decapentanoic acid, is described. Their lipophilicity was estimated applying the Hansch-Leo fragmental procedure and measured by means of reversed phase thin layer chromatography. All compounds were tested for their antibacterial activity against Gram positive and gram negative microorganisms. The less lipophilic compounds showed weak activity, mainly against gram positive microorganisms.
Lipoxygenase inhibitory compounds
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, (2008/06/13)
Compounds of the formulae STR1 wherein n=6-11, M is hydrogen or a pharmaceutically acceptable cation, R is hydrogen or C1 -C6 alkyl optionally substituted by a carboxyl group and Xa, Xb and Xc each independently represent hydrogen or a variety of substituent groups are potent inhibitors of 5-lipoxygenase.
