1172580-57-2Relevant academic research and scientific papers
Sequential addition reactions of two molecules of Grignard reagents to thioformamides
Murai, Toshiaki,Ui, Kazuki,Narengerile
, p. 5703 - 5706 (2009)
(Chemical Equation Presented) Sequential addition reactions of two molecules of Grignard reagents to thioformamides were found to yield tertiary amines in an efficient manner. The addition of two different Grignard reagents can be accomplished by using one equivalent of arylmagnesium reagent in the first step. In the second step, a variety of reagents such as alkyl, alkenyl, aryl, and alkynyl reagents were used to afford the corresponding amines in good to high yields.
