Cas 1172589-01-3,(5R,7R)-4-((S)-4-(aminomethyl)-1'-benzylspiro[indoline-3,3'-pyrrolidine]-1-yl)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol

1172589-01-3

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Basic information

Product Name: (5R,7R)-4-((S)-4-(aminomethyl)-1'-benzylspiro[indoline-3,3'-pyrrolidine]-1-yl)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol
Synonyms: (5R,7R)-4-((S)-4-(aminomethyl)-1'-benzylspiro[indoline-3,3'-pyrrolidine]-1-yl)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol
CAS NO:1172589-01-3
Molecular Formula:
Molecular Weight: 441.576
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (5R,7R)-4-((S)-4-(aminomethyl)-1'-benzylspiro[indoline-3,3'-pyrrolidine]-1-yl)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol(CAS DataBase Reference)
NIST Chemistry Reference: (5R,7R)-4-((S)-4-(aminomethyl)-1'-benzylspiro[indoline-3,3'-pyrrolidine]-1-yl)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol(1172589-01-3)
EPA Substance Registry System: (5R,7R)-4-((S)-4-(aminomethyl)-1'-benzylspiro[indoline-3,3'-pyrrolidine]-1-yl)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol(1172589-01-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1172589-01-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1172589-01-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,2,5,8 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1172589-01:
(9*1)+(8*1)+(7*7)+(6*2)+(5*5)+(4*8)+(3*9)+(2*0)+(1*1)=163
163 % 10 = 3
So 1172589-01-3 is a valid CAS Registry Number.

1172589-01-3Upstream product

1172589-00-2 tert-butyl ((S)-1'-benzyl-1-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)spiro[indoline-3,3'-pyrrolidine]-4-yl)methylcarbamate

1172589-01-3Downstream Products

1172589-02-4 (5R,7R)-4-((S)-1'-benzyl-4-((isopropylamino)methyl)spiro[indoline-3,3'-pyrrolidine]-1-yl)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol

1172589-01-3Relevant academic research and scientific papers

PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS

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Page/Page column 138, (2009/09/04)

The present invention provides compounds of Formula (I) including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as Akt protein kinase inhibitors and for the treatment of Akt-mediated diseases, for example, hyperproliferative diseases such as cancer.

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