117259-23-1

Basic information

• Product Name: 1-AMINO-4-PHENYLCYCLOHEXANECARBOXYLIC ACID
• Synonyms: 1-AMINO-4-PHENYLCYCLOHEXANECARBOXYLIC ACID
• CAS NO: 117259-23-1
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219.28
• Product Categories: pharmacetical
• Mol File: 117259-23-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 387.71 °C at 760 mmHg
• Flash Point: 188.28 °C
• Appearance: /
• Density: 1.161 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 1-AMINO-4-PHENYLCYCLOHEXANECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINO-4-PHENYLCYCLOHEXANECARBOXYLIC ACID(117259-23-1)
• EPA Substance Registry System: 1-AMINO-4-PHENYLCYCLOHEXANECARBOXYLIC ACID(117259-23-1)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 117259-23-1(Hazardous Substances Data)

Usage

General Description

1-AMINO-4-PHENYLCYCLOHEXANECARBOXYLIC ACID is a chemical compound with the molecular formula C13H17NO2. It is an amino acid derivative, and its structure contains a cyclohexane ring with a phenyl group attached to it. 1-AMINO-4-PHENYLCYCLOHEXANECARBOXYLIC ACID has potential applications in pharmaceuticals and medicinal chemistry due to its structural features and potential biological activities. It can be used as a building block in the synthesis of various organic compounds, and its properties make it a valuable tool in drug discovery and development. Further research may reveal its potential therapeutic applications in the treatment of various diseases and disorders.

InChI:InChI=1/C13H17NO2/c14-13(12(15)16)8-6-11(7-9-13)10-4-2-1-3-5-10/h1-5,11H,6-9,14H2,(H,15,16)

Upstream product

• 115005-77-1 8-phenyl-1,3-diazaspiro[4.5]decan-2,4-dione 
• 4894-75-1 1-phenyl-4-cyclohexanone 
• 868140-31-2 2,4-dioxo-8-phenyl-1,3-diaza-spiro[4.5]decane-1,3-dicarboxylic acid di-tert-butyl ester 

Downstream Products

• 365550-63-6 Fmoc-Apc-OH 

Relevant articles and documents

Discovery of 1-amino-4-phenylcyclohexane-1-carboxylic acid and its influence on agonist selectivity between human melanocortin-4 and -1 receptors in linear pentapeptides

Linear pentapeptides (Penta-cis-Apc-DPhe-Arg-Trp-Gly-NH2) containing 1-amino-4-phenylcyclohexane-1-carboxylic acid (cis-Apc) and substituted Apc are potent hMC4R agonists and they are inactive or weakly active in hMC1R, hMC3R, and hMC5R agonist assays. This study, together with our earlier report on 5-BrAtc, demonstrated the importance of replacing His 6 with phenyl-containing rigid templates in achieving good hMC4R agonist potency and selectivity against hMC1R in linear pentapeptides.

Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity

Peptides of formulae I, II and III selectively activate melanocortin-4 (MC-4) receptor activity.