117280-95-2Relevant academic research and scientific papers
Azaspiro compounds and their use
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, (2008/06/13)
Azaspiro compounds of the formula STR1 wherein R1 and R2 independently represent hydrogen, a hydrocarbon residue which may have a substituent, or an acyl group which may have a substituent; R3 represents hydrogen or a hydrocarbon residue which may have a substituent; each of X1 and X2 is oxygen or sulfur; Y represents oxygen, sulfur or a group of the formula: --N(R4)--, wherein R4 represents hydrogen or a lower alkyl group; m represents 0 or 1; n represents 0 or 1, and its salt are novel compounds, possess excellent brain function-improving action, and are of use as drugs for the prevention and therapy of senile dementia of Alzheimer type, vascular-type dementia and dementia derived from Alzheimer's disease, Pick's disease, Huntington's disease, Creutzfeldt-Jakob's disease, Parkinson's disease and spinocerebellar degeneration.
